Product Overview
Purified recombinant protein of Mouse guanylate cyclase activator 2b (retina) (Guca2b), with C-terminal Myc/DDK tag, expressed in HEK293T cells.
Description
This gene encodes a member of the guanylin family and preproprotein that is proteolytically processed to generate a mature protein product. The mature protein product, known as uroguanylin, is an endogenous ligand for the guanylate cyclase-C receptor and may regulate salt and water homeostasis in the intestine and kidneys. Homozygous knockout mice for this gene exhibit impaired sodium chloride excretion and elevated arterial pressure. This gene is present in a gene cluster with a related guanylin family member on chromosome 4. [provided by RefSeq, Sep 2015]
Form
25mM Tris.HCl, pH 7.3, 100mM glycine, 10% glycerol
