Recombinant Mouse IFNAR1 Protein (Glu27-Thr429), C-10×His-tagged
Product Description
Cat
IMP-10429
Official Symbol
Ifnar1
Product Overview
Recombinant Mouse IFN-alpha/beta R1 protein (Glu27-Thr429) with a C-terminal 10-His tag was expressed in Mouse myeloma cell line.
Description
The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor.
Expression System
Mouse myeloma cell line
Species
Mouse
Tag
C-10×His
Predicted N Terminal
Glu27
Form
Lyophilized from a 0.2 μm filtered solution in PBS.
Molecular Mass
Predicted Molecular Mass: 47.1 kDa
SDS-PAGE: 60-70 kDa, reducing conditions
Protein length
Glu27-Thr429
Bio-activity
Measured by its ability to inhibit Limitin-mediated protection of L-929 mouse fibroblast cells viral lysis. The ED50 for this effect is 0.3-1.2 μg/mL in the presence of 30 pg/mL of Recombinant Mouse Limitin/IFN-zeta.
Endotoxin
<0.10 EU/μg of the protein by the LAL method.
Purity
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining.
Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution
Reconstitute at 100 μg/mL in sterile PBS.
Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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