Product Overview
Purified recombinant protein of Mouse interleukin 10 (Il10), with C-terminal Myc/DDK tag, expressed in HEK293T cells.
Description
This gene encodes an anti-inflammatory cytokine that is a member of the class-2 cytokine family. The encoded protein is secreted by cells of both the innate and adaptive immune systems and is crucial for limiting the immune response to a broad range of pathogens. It also has been shown to suppress autoimmune responses. This protein mediates it's immunosuppressive signal through a specific interleukin 10 receptor complex. Aberrant functioning of this gene is associated with numerous immune disorders including graft-versus-host disease, and increased susceptibility to HIV-1 infection and rheumatoid arthritis. [provided by RefSeq, Sep 2015]
Form
25mM Tris.HCl, pH 7.3, 100mM glycine, 10% glycerol
