Recombinant Mouse LGR6 Protein (Gly23-Ala567), C-mFc-tagged
Product Description
Cat
IMP-9907
Official Symbol
Lgr6
Product Overview
Recombinant Mouse Lgr6 protein (Gly23-Ala567) with a Mouse IgG2A (Glu98-Lys330) Fc tag at C-terminus was expressed in Chinese Hamster Ovary cell line.
Description
This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily. The encoded protein is a glycoprotein hormone receptor with a large N-terminal extracellular domain that contains leucine-rich repeats important for the formation of a horseshoe-shaped interaction motif for ligand binding. Alternative splicing of this gene results in multiple transcript variants.
Expression System
CHO
Species
Mouse
Tag
C-mFc
Predicted N Terminal
Gly23
Form
Lyophilized from a 0.2 μm filtered solution in PBS.
Molecular Mass
Predicted Molecular Mass: 87.9 kDa (monomer)
SDS-PAGE: 95-105 kDa, reducing conditions
Protein length
Gly23-Ala567
Bio-activity
Measured by its binding ability in a functional ELISA. When Recombinant Mouse R-Spondin 3 is coated at 0.5 μg/mL, Recombinant Mouse Lgr6 Fc Chimera binds with an apparent Kd <1.0 nM.
Endotoxin
<0.01 EU/μg of the protein by the LAL method.
Purity
>95%, by SDS-PAGE with silver staining, under reducing conditions.
Notes
Disulfide-linked homodimer
Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution
Reconstitute at 200 μg/mL in PBS.
Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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