Recombinant Mouse Pvr protein, C-hFc-Avi Tag
Product Description
Cat
IMP-336
Official Symbol
Pvr
Product Overview
Recombinant Mouse Pvr protein (NP_081790.1) (Met1-Arg345) was expressed in HEK293, fused with a C-terminal Fc region of human IgG1 tagged AVI tag at the C-terminus.
Description
CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. The normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. CD155 may assist in an efficient humoral immune response generated within the intestinal immune system. It has been demonstrated that CD155 can be recognized and bond by DNAM-1 and CD96 which promote the adhesion, migration and NK-cell killing, and thus efficiently prime cell-mediated tumor-specific immunity.
Expression System
HEK293
Species
Mouse
Tag
C-hFc-Avi Tag
Predicted N Terminal
Asp 29
Form
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Molecular Mass
The recombinant Mouse Pvr consists of 570 amino acids and predicts a molecular mass of 62.9 kDa.
Protein length
Met1-Arg345
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
Purity
> 90 % as determined by SDS-PAGE.
Storage
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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