Recombinant Mouse Tnfrsf9(NP_001070976.1)(Val24-Leu187) is expressed in HEK293, fused with a Fc tag at the C-terminus.
Description
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is a member of the tumor necrosis factor (TNF) receptor family. It can be induced by lymphocyte activation (ILA) and is expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, TNFRSF9 expression is found on dendritic cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. As receptor for TNFSF9/4-1BBL, it can activate T cells and the cross-linking of this protein can enhance T cell proliferation, IL-2 secretion survival and cytolytic activity. Further, it can enhance immune activity to eliminate tumors in mice.
Expression System
HEK293
Species
Mouse
Tag
C-Fc Tag
Form
Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
Molecular Mass
60-70 kDa, reducing conditions.
Protein length
Val24-Leu187
Endotoxin
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Storage
Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
Concentration
Please refer to product label for detailed information.
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