Recombinant Mouse Vsir Protein, C-Myc/DDK-tagged

Product Description

Cat

IMP-7862

Official Symbol

Vsir

Product Overview

Purified recombinant protein of Mouse V-set immunoregulatory receptor (Vsir), transcript variant 2, with C-terminal Myc/DDK tag, expressed in HEK293T cells.

Description

Immunoregulatory receptor which inhibits the T-cell response (PubMed: 21383057, PubMed: 24743150, PubMed: 25267631). May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling (PubMed: 20042595). May stimulate MMP14-mediated MMP2 activation (By similarity).[UniProtKB/Swiss-Prot Function]

Expression System

HEK293T

Species

Mouse

Tag

C-Myc/DDK

Form

25mM Tris.HCl, pH 7.3, 100mM glycine, 10% glycerol

Molecular Mass

33.6 kDa

AA Sequence

MGVPAVPEASSPRWGTLLLAIFLAASRGLVAAFKVTTPYSLYVCPEGQNATLTCRILGPVSKGHDVTIYKTWYLSSRGEVQMCKEHRPIRNFTLQHLQHHGSHLKANASHDQPQKHGLELASDHHGNFSITLRNVTPRDSGLYCCLVIELKNHHPEQRFYGSMELQVQAGKGSGSTCMASNEQDSDSITAAALATGACIVGILCLPLILLLVYKQRQVASHRRAQELVRMDSNTQGIENPGFETTPPFQGMPEAKTRPPLSYVAQRQPSESGRYLLSDPSTPLSPPGPGDVFFPSLDPVPDSPNSEAITRTRPLEQKLISEEDLAANDILDYKDDDDKV

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining.

Storage

Store at -80 centigrade after receiving vials.
Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Concentration

> 50 μg/mL as determined by microplate BCA method.

Data Sheet MSDS

Datasheet MSDS

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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