Recombinant Mouse Vsir Protein, C-Myc/DDK-tagged

Product Description

Cat

IMP-7862

Official Symbol

Vsir

Product Overview

Purified recombinant protein of Mouse V-set immunoregulatory receptor (Vsir), transcript variant 2, with C-terminal Myc/DDK tag, expressed in HEK293T cells.

Description

Immunoregulatory receptor which inhibits the T-cell response (PubMed: 21383057, PubMed: 24743150, PubMed: 25267631). May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling (PubMed: 20042595). May stimulate MMP14-mediated MMP2 activation (By similarity).[UniProtKB/Swiss-Prot Function]

Expression System

HEK293T

Species

Mouse

Tag

C-Myc/DDK

Form

25mM Tris.HCl, pH 7.3, 100mM glycine, 10% glycerol

Molecular Mass

33.6 kDa

AA Sequence

MGVPAVPEASSPRWGTLLLAIFLAASRGLVAAFKVTTPYSLYVCPEGQNATLTCRILGPVSKGHDVTIYKTWYLSSRGEVQMCKEHRPIRNFTLQHLQHHGSHLKANASHDQPQKHGLELASDHHGNFSITLRNVTPRDSGLYCCLVIELKNHHPEQRFYGSMELQVQAGKGSGSTCMASNEQDSDSITAAALATGACIVGILCLPLILLLVYKQRQVASHRRAQELVRMDSNTQGIENPGFETTPPFQGMPEAKTRPPLSYVAQRQPSESGRYLLSDPSTPLSPPGPGDVFFPSLDPVPDSPNSEAITRTRPLEQKLISEEDLAANDILDYKDDDDKV

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining.

Storage

Store at -80 centigrade after receiving vials.
Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Concentration

> 50 μg/mL as determined by microplate BCA method.

Data Sheet MSDS

Datasheet MSDS

For research or industrial raw materials, not for personal medical use!

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