Recombinant Rat ACE2 Protein (Met1-Thr740), C-10×His-tagged
Product Description
Cat
IMP-10649
Official Symbol
ACE2
Product Overview
Recombinant Rat ACE-2 protein (Met1-Thr740) with a C-terminal 10-His tag was expressed in Mouse myeloma cell line.
Description
Enables carboxypeptidase activity. Involved in maternal process involved in female pregnancy; negative regulation of ERK1 and ERK2 cascade; and negative regulation of smooth muscle cell proliferation. Located in extracellular space and membrane. Used to study glaucoma; myocardial infarction; and thrombosis. Biomarker of hypertension; lung disease; middle cerebral artery infarction; myocardial infarction; and primary biliary cholangitis. Human ortholog(s) of this gene implicated in several diseases, including avian influenza; cerebral malaria; hypertension (multiple); respiratory syncytial virus infectious disease; and severe acute respiratory syndrome. Orthologous to human ACE2 (angiotensin converting enzyme 2).
Expression System
Mouse myeloma cell line
Species
Rat
Tag
C-10×His
Predicted N Terminal
No results obtained: Gln18 predicted
Form
Supplied as a 0.2 μm filtered solution in Tris, NaCl, ZnCl2 and Glycerol.
Molecular Mass
Predicted Molecular Mass: 85 kDa
SDS-PAGE: 120 kDa, reducing conditions
Protein length
Met1-Thr740
Bio-activity
Measured by its ability to cleave a fluorogenic peptide substrate, Mca-YVADAPK(Dnp)-OH. The specific activity is >300 pmol/min/μg, as measured under the described conditions.
Endotoxin
<1.0 EU/μg of the protein by the LAL method.
Purity
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
6 months from date of receipt, -20 to -70 centigrade as supplied.
3 months, -20 to -70 centigrade under sterile conditions after opening.
Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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