Recombinant Rat Fcgr2b Protein, C-His-tagged

Product Description

Cat

IMP-4211

Official Symbol

Fcgr2b

Product Overview

Recombinant rat FCGR2B (Q63203-1) extracellular domain (Met 1-Pro 212) was expressed, fused with a polyhistidine tag at the C-terminus.

Description

The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.

Expression System

HEK293

Species

Rat

Tag

C-His

Predicted N Terminal

His 32

Form

Lyophilized from sterile PBS, pH 7.4, 5 % trehalose, 5% mannitol and 0.01% Tween80.

Molecular Mass

The recombinant rat FCGR2B comprises 192 amino acids and predicts a molecular mass of 21.9 kDa. The apparent molecular mass of the rat FCGR2B is approximately 35-40 kDa in SDS-PAGE under reducing conditions due to glycosylation.

Protein length

Met1-Pro212

Endotoxin

< 1.0 EU/μg of the protein as determined by the LAL method

Purity

> 97 % as determined by SDS-PAGE

Storage

Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Reconstitution

A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

SDS-PAGE

Bioactivity-ELISA 1

Measured by its ability to bind human IgG1, Biotinylatedin a functional ELISA.

Data Sheet MSDS

Datasheet MSDS

For research or industrial raw materials, not for personal medical use!

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