Recombinant Rat Fcgr2b Protein, C-His-tagged

Product Description

Cat

IMP-4211

Official Symbol

Fcgr2b

Product Overview

Recombinant rat FCGR2B (Q63203-1) extracellular domain (Met 1-Pro 212) was expressed, fused with a polyhistidine tag at the C-terminus.

Description

The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.

Expression System

HEK293

Species

Rat

Tag

C-His

Predicted N Terminal

His 32

Form

Lyophilized from sterile PBS, pH 7.4, 5 % trehalose, 5% mannitol and 0.01% Tween80.

Molecular Mass

The recombinant rat FCGR2B comprises 192 amino acids and predicts a molecular mass of 21.9 kDa. The apparent molecular mass of the rat FCGR2B is approximately 35-40 kDa in SDS-PAGE under reducing conditions due to glycosylation.

Protein length

Met1-Pro212

Endotoxin

< 1.0 EU/μg of the protein as determined by the LAL method

Purity

> 97 % as determined by SDS-PAGE

Storage

Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Reconstitution

A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

SDS-PAGE

Bioactivity-ELISA 1

Measured by its ability to bind human IgG1, Biotinylatedin a functional ELISA.

Data Sheet MSDS

Datasheet MSDS

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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