Recombinant Rhesus IL17A&IL17F Protein, C-His-tagged

Product Description

Cat

IMP-4656

Official Symbol

IL17A&IL17F

Product Overview

Recombinant rhesus IL17A (XP_001106391.1) (Met 1-Ala 155) and the mature form of rhesus IL17F (NP_001248216.1) (Arg 31-Gln 163) linked by a polypeptide linker was expressed with a polyhistidine tag at the C-terminus.

Description

The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1.

Expression System

HEK293

Species

Rhesus

Tag

C-His

Predicted N Terminal

Gly 24

Form

Lyophilized from sterile PBS, pH 7.4, 5 % trehalose, 5% mannitol and 0.01% Tween80.

Molecular Mass

The recombinant rhesus IL17A&IL17F consists of 291 amino acids and predicts a molecular mass of 32.5 kDa.

Protein length

Met1-Ala155 and Arg31-Gln163

Endotoxin

< 1.0 EU/μg of the protein as determined by the LAL method

Purity

> 95 % as determined by SDS-PAGE

Storage

Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Reconstitution

A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

SDS-PAGE

Data Sheet MSDS

Datasheet MSDS

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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