Description
NSP8 is a nonstructural protein of coronavirus. NSP8 acts as a primase in RNA synthesis. NSP8 and NSP7 are essential co-factors of NSP12 (the catalytic subunit with RNA-dependent RNA polymerase activity) that can remarkably stimulate RdRp activity. The nsp12-nsp7-nsp8 subcomplex is defined as the minimal core component for mediating coronavirus RNA synthesis.
Form
Lyophilized from sterile 50 mM Tris, 500 mM NaCl, pH 7.4, 5 % trehalose, 5% mannitol and 0.01% Tween80.
