Recombinant Human FCGR2B Protein (Ala46-Pro217), C-10×His-tagged
Product Description
Cat
IMP-9703
Official Symbol
FCGR2B
Product Overview
Recombinant human Fc gamma RIIB/C (CD32b/c) protein (Ala46-Pro217) with a C-terminal 10-His tag was expressed in Mouse myeloma cell line.
Description
The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.
Expression System
Mouse myeloma cell line
Species
Human
Tag
C-10×His
Predicted N Terminal
Ala46
Form
Lyophilized from a 0.2 μm filtered solution in PBS.
Molecular Mass
Predicted Molecular Mass: 21 kDa
SDS-PAGE: 25-35 kDa, reducing conditions
Protein length
Ala46-Pro217
Bio-activity
Measured by its ability to bind human IgG with an estimated Kd <200 nM.
Endotoxin
<1.0 EU/μg of the protein by the LAL method.
Purity
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining.
Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution
Reconstitute at 100 μg/mL in sterile PBS.
SDS-PAGE
SDS-PAGE

Bioactivity-ELISA 1
Bioactivity

Measured by its ability to bind human IgG with an estimated Kd <200 nM.

Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

Online Inquiry
Contact Info